Table 1.
Healthy controls (N = 490) | Schizophrenia patients (N = 122) | p value* | d′ | |
---|---|---|---|---|
Mean ± SD | Mean ± SD | |||
Demographics | ||||
Age (years) | 32.0 ± 14.5 | 35.6 ± 12.1 | 0.01 | 0.26 |
Sex (male/female) | 265/225 | 60/62 | 0.33** | |
Education (years) | 14.8 ± 1.8 | 14.0 ± 2.6 | < 0.001 | 0.41 |
Current IQ | 113.3 ± 12.1 | 88.7 ± 15.9 | < 0.001 | 1.91 |
Estimated premorbid IQ | 102.6 ± 9.2 | |||
Cognitive decline | − 13.9 ± 12.4 | |||
Onset age (years) | 22.9 ± 10.4 | |||
Duration of illness (years) | 12.6 ± 9.9 | |||
Symptoms | ||||
PANSS total | 83.5 ± 20.2 | |||
PANSS positive | 19.1 ± 5.7 | |||
PANSS negative | 20.9 ± 5.1 | |||
PANSS general | 43.5 ± 10.6 | |||
Drug (mg/day) | ||||
CPZ eq. | 531.4 ± 513.7 | |||
Typical antipsychotic eq. | 158.4 ± 363.3 | |||
Atypical antipsychotic eq. | 376.0 ± 489.1 | |||
Diazepam eq. | 7.9 ± 12.0 | |||
Biperiden eq. | 0.8 ± 1.2 |
*Based on t-test except for Sex, **χ2-test.
PANSS Positive and Negative Syndrome Scale, CPZ eq. chlorpromazine equivalents.