Table 2.
Return saccade probability | Exploration area | |||||
---|---|---|---|---|---|---|
Coefficient | Adjusted R2 | p value | Coefficient | Adjusted R2 | p value | |
Healthy controls (N = 490) | ||||||
Demographics | ||||||
Age (years) | 0.003 | 0.009 | 0.07 | − 0.005 | 0.029 | < 0.001 |
Education (years) | − 0.011 | 0.000 | 0.99 | 0.023 | 0.008 | 0.41 |
Current IQ | − 0.006 | 0.029 | 0.001 | 0.007 | 0.039 | < 0.001 |
Schizophrenia (N = 122) | ||||||
Demographics | ||||||
Age (years) | − 0.001 | − 0.008 | 1.00 | − 0.008 | 0.009 | 1.00 |
Education (years) | 0.000 | − 0.008 | 1.00 | − 0.015 | − 0.005 | 1.00 |
Current IQ* | − 0.009 | 0.033 | 0.21 | 0.008 | 0.026 | 0.49 |
Estimated premorbid IQ* | 0.004 | − 0.005 | 1.00 | 0.001 | − 0.008 | 1.00 |
Cognitive decline* | − 0.014 | 0.105 | 0.02 | 0.015 | 0.041 | 0.07 |
Onset age (years) | 0.000 | − 0.008 | 1.00 | 0.000 | − 0.008 | 1.00 |
Duration of illness (years) | − 0.001 | − 0.008 | 1.00 | − 0.001 | − 0.008 | 1.00 |
Symptoms | ||||||
PANSS total | 0.003 | − 0.003 | 1.00 | 0.003 | − 0.003 | 1.00 |
PANSS positive | − 0.001 | − 0.008 | 1.00 | − 0.001 | − 0.008 | 1.00 |
PANSS negative | 0.021 | 0.008 | 0.78 | 0.021 | 0.008 | 0.78 |
PANSS general | 0.007 | − 0.002 | 1.00 | 0.007 | − 0.002 | 1.00 |
Drug (mg/day) | ||||||
CPZ eq. | 0.000 | − 0.008 | 1.00 | 0.000 | − 0.008 | 1.00 |
Typical antipsychotic eq. | 0.000 | 0.007 | 1.00 | 0.000 | 0.007 | 1.00 |
Atypical antipsychotic eq.* | 0.000 | 0.004 | 1.00 | 0.000 | 0.004 | 1.00 |
Diazepam eq.* | − 0.003 | − 0.005 | 1.00 | − 0.003 | − 0.005 | 1.00 |
Biperiden eq.* | − 0.118 | 0.044 | 0.45 | − 0.118 | 0.044 | 0.45 |
Bonferroni-corrected p values (raw p value × 3 for HCs, × 16 for SZs) and adjusted R2 are shown. A negative adjusted R2 is interpreted as zero variance explained. Bold underlined values highlight statistically significant contributions (p < 0.05).
*In SZs, N = 121 for current IQ, estimated premorbid IQ, cognitive decline, and atypical antipsychotic eq., N = 94 for diazepam eq., and N = 80 for biperiden eq.
PANSS Positive and Negative Syndrome Scale, CPZ eq. chlorpromazine equivalents.