Skip to main content
. 2021 Feb 5;11:3237. doi: 10.1038/s41598-021-82253-w

Table 2.

Regression coefficients for return saccade probability and exploration area explained by the demographic and clinical characteristics of HCs and SZs.

Return saccade probability Exploration area
Coefficient Adjusted R2 p value Coefficient Adjusted R2 p value
Healthy controls (N = 490)
Demographics
 Age (years) 0.003 0.009 0.07 − 0.005 0.029 < 0.001
 Education (years) − 0.011 0.000 0.99 0.023 0.008 0.41
 Current IQ − 0.006 0.029 0.001 0.007 0.039 < 0.001
Schizophrenia (N = 122)
Demographics
 Age (years) − 0.001 − 0.008 1.00 − 0.008 0.009 1.00
 Education (years) 0.000 − 0.008 1.00 − 0.015 − 0.005 1.00
 Current IQ* − 0.009 0.033 0.21 0.008 0.026 0.49
 Estimated premorbid IQ* 0.004 − 0.005 1.00 0.001 − 0.008 1.00
 Cognitive decline* − 0.014 0.105 0.02 0.015 0.041 0.07
 Onset age (years) 0.000 − 0.008 1.00 0.000 − 0.008 1.00
 Duration of illness (years) − 0.001 − 0.008 1.00 − 0.001 − 0.008 1.00
Symptoms
 PANSS total 0.003 − 0.003 1.00 0.003 − 0.003 1.00
 PANSS positive − 0.001 − 0.008 1.00 − 0.001 − 0.008 1.00
 PANSS negative 0.021 0.008 0.78 0.021 0.008 0.78
 PANSS general 0.007 − 0.002 1.00 0.007 − 0.002 1.00
Drug (mg/day)
 CPZ eq. 0.000 − 0.008 1.00 0.000 − 0.008 1.00
 Typical antipsychotic eq. 0.000 0.007 1.00 0.000 0.007 1.00
 Atypical antipsychotic eq.* 0.000 0.004 1.00 0.000 0.004 1.00
 Diazepam eq.* − 0.003 − 0.005 1.00 − 0.003 − 0.005 1.00
 Biperiden eq.* − 0.118 0.044 0.45 − 0.118 0.044 0.45

Bonferroni-corrected p values (raw p value × 3 for HCs, × 16 for SZs) and adjusted R2 are shown. A negative adjusted R2 is interpreted as zero variance explained. Bold underlined values highlight statistically significant contributions (p < 0.05).

*In SZs, N = 121 for current IQ, estimated premorbid IQ, cognitive decline, and atypical antipsychotic eq., N = 94 for diazepam eq., and N = 80 for biperiden eq.

PANSS Positive and Negative Syndrome Scale, CPZ eq. chlorpromazine equivalents.