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. 2020 Jun;14(2):81–87. doi: 10.18502/jfrh.v14i2.4349

Table 3.

Detection rate of age, ultrasound, and serum biochemical factors among the Iranian pregnant women

Characters (n = 1500) n(%) Risk ≥ 1:250 [n(%)] Detection rate [n(%)]
Trisomy 21 Trisomy 18 Trisomy 13
Maternal age
      17 ≤ age ≤ 20 30 (2) 5 2/30: %6.6 0 (0) 0 (0)
      20 ≤ age ≤ 30 720 (48) 158 8/30: %26.6 2/5: %40 1/2: %50
      30 ≤ age ≤ 40 600 (40) 167 18/30: %60 3/5: %60 1/2:%50
      ≥ 40 150 (10) 42 2/30: %6.6 0 (0) 0 (0)
NT ≥ 3 105 (7) 40 2/30: %6.6 3/5: %60 1/2: %50
Absent of nasal bone 15 (1) 9 13/30: %42.4 2/5: %40 0 (0)
fβ-hCG ≥ 2 MoM 100 (6) 21 10/30: %33.33 0 (0) 0 (0)
PAPP-A ≤ 0.5 MoM 102 (6.8) 28 6/30: %17.8 3/5: %60 2/2:%100
Tricuspid regurgitation 9 (0.6) 5 12/30: % 36.3 4/5:80 0 (0)

MOM: Multiple of median, fβ-hCG: Free beta human chronic gonadotropin, PAPP-A: Pregnancy associated protein