Table 4.
Comparison of frequency of various pregnancy complications between samples with the cutoff points of PAPP-A and Β-HCG
|
Papp-A
≤ 0.4 |
Papp-A
> 2 |
OR (95% CI) |
P-
value |
Fβ-hCG ≤
0.5 |
Fβ-hCG >
2 |
OR (95% CI) |
P-
value |
|
|---|---|---|---|---|---|---|---|---|
| IUGR | 277 (18.5) | 27 (1.8) | 2.13 (0.32-7.13) | < 0.001 | 73 (4.9) | 47 (3.1) | 1.02 (0.2-1.2) | 0.07 |
| Normal growth |
1222 (81.5) | 1473 (98.2) | 1427 (95.1) | 1453 (96.9) | ||||
| Pre-term Labor |
222 (14.8) | 98 (6.5) | 1.76 (0.11-6.1) | < 0.001 | 61 (4.06) | 39 (2.65) | 0.78 (0.22-0.65) | 0.23 |
| Term-labor | 1278 (85.2) | 1402 (93.5) | 1483 (98.86) | 1461 (97.4) | ||||
| Different types of fetal loss | ||||||||
| IUFD | 132 (8.8) | 22. (1.5) | 1.9 (0.44-2.1) | 0.03 | 79 (5.3) | 13 (2.2) | 0.92 (0.2-0.87) | 0.12 |
| Normal pregnancy |
1368(91.2) | 1477 (98.5) | 14205 (94.7) | 1467 (97.8) | ||||
| Abortion | 18(1.2) | 5205(3.5) | 0.84 (0.11-0.87) | 0.089 | 127 (8.47) | 28 (1.9) | 2.92 (0.85-6.1) | 0.003 |
| Not abortion | 1482(98.8) | 1477 (96.5) | 1372 (91.53) | 1483 (98.9) | ||||
| Elective termination |
34 (2.3) | 7 (0.5) | 0.3 (0.1-0.75) | 0.12 | 46 (3.1) | 16 (1.12) | 0.12 (0.01-1.1) | 0.34 |
| Not elective termination |
1465 (97.7) | 1492 (99.5) | 1453 (96.9) | 1483 (98.9) | ||||
P-value shows comparison results of between high and low levels of serum markers. (Logistic regression analyses test). Fβ-hCG: Free beta human chronic gonadotropin, PAPP-A: Pregnancy associated protein A, IUFD: Intra uterine fetal death, IUGR: Intra uterine growth retardation.