Skip to main content
. 2021 Jan 25;22(3):1172. doi: 10.3390/ijms22031172

Figure 1.

Figure 1

Preparation of the Pheo a/EAE7-conjugated γ-PGA/MPEG-PLGA/HA (PPHE) polymeric nanoparticles. Schematic diagram of the –synthetic process of the (a) Pheo a-conjugated γ-PGA (γ-PGA-Pheo a) prepared through the carbodiimide reaction to form amide linkage, (b) self-assembled γ-PGA-Pheo a/MPEG-PLGA (PP) nanoparticles, and (c) targeting ligand EAE7-decorated HA (HA-EAE7)-containing PPHE polymeric nanoparticles prepared via the amide bone formation and layer-by-layer (LBL) self-assembly method.