FLS	fibroblast-like synoviocyte
LPS	lipopolysaccharide
iNOS	inducible nitric oxide synthase
COX	cyclooxygenase
TLR	toll-like receptor
IL	interleukin
TNF	tumor necrosis factor
NLRP3	the NOD-, LRR- and pyrin domain-containing protein 3
ASC	the adaptor molecule apoptosis-associated speck-like protein containing a CARD
JAK	Janus-associated kinase
FDA	the US Food and Drug Administration
BTK	Bruton’s tyrosine kinase
MAPK	mitogen-activated protein kinase
XTT	2,3-bis-(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide
TAK1	transforming growth factor-β-activated kinase 1
IKK	inhibitor of NF-κB kinase
OA	osteoarthritis
HRP	horseradish peroxidase
FBS	fetal bovine serum
IRB	the Institutional Review Board
DMEM	Dulbecco’s modified Eagle medium
OD	optical density
TBS	Tris-buffered saline
RT-PCR	reverse transcription-polymerase chain reaction
qPCR	quantitative PCR
Ct	the threshold cycle number
SPSS	the Statistical Package for Social Science