Table 4.
Anti-inflammatory effects of C. europaea fractions on carrageenan-induced paw edema.
| Treatment Groups | Basal Diameter (cm) |
Paw Size after the Carrageenan Injection (Mean ± SEM)/Percent Inhibition of Edema | |||
|---|---|---|---|---|---|
| 3 Hour | 4 Hour | 5 Hour | 6 Hour | ||
| NaCl | 2.3 ± 0.01581 |
2.6 ± 0.04472 |
2.8 ± 0.0547 |
2.68 ± 0.0158 |
2.520 ± 0.0209 |
| Indomethacin® 10 mg/kg |
2.220 ± 0.03742 |
2.420 ± 0.03742 ** 33.33% |
2.362 ± 0.0348 * 71.60% |
2.300 ± 0.0273 78.95% |
2.266 ± 0.0331 79.09% |
| ET CE 100 mg/kg |
2.340 ± 0.02449 |
2.556 ± 0.0250 *** 28% |
2.534 ± 0.0271 *** 61.20% |
2.474 ± 0.0208 ** 64.74% |
2.398 ± 0.0217 73.64% |
| Poly CE 50 mg/kg |
2.315 ± 0.00866 |
2.523 ± 0.0062 *** 30.38% |
2.473 ± 0.0062 *** 68.5% |
2.410 ± 0.0070 *** 75% |
2.369 ± 0.0060 *** 75.68% |
| But CE 100 mg/kg |
2.350 ± 0.02887 |
2.555 ± 0.0295 *** 31.67% |
2.503 ± 0.0246 ** 69.50% |
2.440 ± 0.0291 76.32% |
2.401 ± 0.0282 76.70% |
Values are expressed as means ± SEM. (n = 5), p < 0.05 considered statistically significant compared to the control and reference drug (indomethacin 10 mg/mL). *: Significant, **: high significant; ***: extremely significant.