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. 2021 Jan 24;22(3):1148. doi: 10.3390/ijms22031148

Table 2.

GO terms significantly enriched from differentially expressed genes between rats with depressive-like behavior and control group in the amygdala.

GO Accession GO Term Corr p No. Genes
Downregulated
GO:0007610 behavior 0.002 26
GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway 0.002 12
GO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger 0.003 12
GO:0044459 plasma membrane part 0.004 53
GO:0003013 circulatory system process 0.004 17
GO:0008015 blood circulation 0.004 17
GO:0007626 locomotory behavior 0.004 14
GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway 0.037 7
Upregulated
GO:0023052 signaling 0.000 102
GO:0007154 cell communication 0.000 102
GO:0007165 signal transduction 0.000 95
GO:0038023 signaling receptor activity 0.001 55
GO:0060089 molecular transducer activity 0.001 55
GO:0004888 transmembrane signaling receptor activity 0.001 52
GO:0004871 signal transducer activity 0.006 57
GO:0007186 G-protein coupled receptor signaling pathway 0.006 49
GO:0003008 system process 0.006 57
GO:0051606 detection of stimulus 0.017 37
GO:0050896 response to stimulus 0.022 126
GO:0004930 G-protein coupled receptor activity 0.028 40
GO:0009593 detection of chemical stimulus 0.028 34
GO:0050906 detection of stimulus involved in sensory perception 0.045 34
GO:0009653 anatomical structure morphogenesis 0.050 45