Table 1.
Effects on testis weight, testosterone, mean tubular diameter (MTD) and Johnsen’s score (JS) induced by Se (0.4 mg/kg i.p.), PDRN (8 mg/Kg/day i.p.) and Se (0.4 mg/kg i.p.) plus PDRN (8 mg/Kg/ day i.p.) in varicocele rats as compared to sham and varicocele rats. Se = seleno-L-methionine; PDRN = polydeoxyribonucleotide; CL = contralateral testis. All values are expressed as mean ± SE; n = 7 animals for each group. a p < 0.05 vs. sham; b p < 0.05 vs. varicocele.
| Groups | Testis Weight (g) | Testosterone (ng/ml) |
MTD (μm) | JS |
|---|---|---|---|---|
| Sham | 1.65 ± 0.17 | 6.1 ± 0.9 | 249 ± 21 | 9.7 ± 0.2 |
| Varicocele | 0.83 ± 0.11 a | 2.6 ± 0.5 a | 127 ± 19 a | 2.6 ± 0.5 a |
| Varicocele CL | 1.12 ± 0.36 a,b | 168 ± 15 a,b | 7.3 ± 0.8 a,b | |
| Varicocele + Se | 1.18 ± 0.25 a,b | 4.2 ± 0.8 a,b | 173 ± 12 a,b | 6.7 ± 0.7 a,b |
| Varicocele + Se CL | 1.39 ± 0.33 a,b | 203 ± 16 a,b | 8.8 ± 0.6 b | |
| Varicocele + PDRN | 1.28 ± 0.10 a,b | 5.1 ± 0.5 b | 210 ± 15 a,b | 8.4 ± 1.3 b |
| Varicocele + PDRN CL | 1.55 ± 0.51 b | 221 ± 13 b | 9.1 ± 0.7 b | |
| Varicocele + PDRN + Se | 1.58 ± 0.35 b | 5.9 ± 0.7 b | 242 ± 17 b | 9.0 ± 0.5 b |
| Varicocele + PDRN + Se CL | 1.62 ± 0.39 b | 251 ± 14 b | 9.3 ± 0.5 b |