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. 2021 Jan 28;22(3):1299. doi: 10.3390/ijms22031299

Figure 2.

Figure 2

Hormonal assay for testosterone. (A) Plasma total testosterone levels in wild-type (WT, white diamonds); control (CON, black diamonds); 15 mg/kg streptozotocin (STZ-15, bright orange rectangles); 30 mg/kg streptozotocin (STZ-30, dark orange triangles); and 60 mg/kg streptozotocin (STZ-60, red circles) groups. Mice in the STZ-15 and STZ-30 groups developed hyperandrogenism. (B) Plasma luteinizing hormone (LH) levels. Treatment with STZ injections did not elevate circulating LH levels. (C) Estradiol (E2) levels. Treatment with STZ injections did not suppress E2 synthesis. (a) significant differences compared with the WT group; (b) significant differences compared with the CON group. n.s., not significant.