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. 2021 Jan 28;22(3):1299. doi: 10.3390/ijms22031299

Figure 3.

Figure 3

Polycystic ovary syndrome (PCOS) phenotype of STZ-treated mice ovary. (A) Ovary weight in wild-type (WT, white diamonds); control (CON, black diamonds); 15 mg/kg streptozotocin (STZ-15, bright orange rectangles); 30 mg/kg streptozotocin (STZ-30, dark orange triangles); and 60 mg/kg streptozotocin (STZ-60, red circles) groups. (B) Representative microscopic images of ovary sections (hematoxylin and eosin staining; scale bar = 1000 μm). (C) The number of antral follicles per ovary indicating multi follicular formation in the ovaries of mice in the STZ-15 and STZ-30 groups. (D) The number of atretic follicles per ovary indicating that STZ injections compromised ovarian functions. (E) The number of corpora lutea per ovary showing the decreased abundance of corpora lutea in the STZ-60 group. (a) significant differences compared with the WT group; (b) significant differences compared with the CON group; (c) significant differences compared with the STZ-15 group; (d) significant differences compared with the STZ-30 group; n.s., not significant.