Table 5.
Effect of extracts of dried peel powders (DP) extracts of M. jaboticaba (DP-MJ), S. cumini (DP-SC), and S. malaccense (DP-SM) (500–1000 µg/mL) on programmed cell death in adenocarcinoma cell line after 24 h.
| Stages of Cell Death | CT | DP-MJ (µg/mL) | DP-SC (µg/mL) | DP-SM (µg/mL) | |||
|---|---|---|---|---|---|---|---|
| 500 | 1000 | 500 | 1000 | 500 | 1000 | ||
| Viable cells (Annexin V−/PI−) |
95.50 ± 1.25 | 89.52 ± 0.47 * | 87.9 ± 3.00 * | 92.8 ± 2.00 | 91.00 ± 0.80 | 90.60 ± 0.62 | 91.95 ± 0.95 |
| Early apoptosis (Annexin V+/PI−) |
2.51 ± 0.78 | 6.88 ± 0.10 * | 7.25 ± 2.72 * | 2.27 ± 0.23 | 2.58 ± 0.22 | 3.00 ± 0.40 | 2.80 ± 0.86 |
| Late apoptosis (Annexin V+/PI+) |
1.57 ± 0.85 | 3.61 ± 0.09 * | 4.03 ± 0.13 ** | 1.08 ± 1.09 | 0.98 ± 0.40 | 0.82 ± 0.25 | 1.27 ± 0.11 |
| Non-apoptotic cells (Annexin V−/PI+) |
4.04 ± 1.08 | 2.62 ± 0.11 * | 1.77 ± 1.14 * | 1.84 ± 0.66 * | 5.45 ± 1.01 | 5.60 ± 1.02 | 3.97 ± 0.97 |
Results are expressed as a percentage of total cells. Significant differences between untreated cells (CT) and cells treated with DP-MJ, DP-SC, and DP-SM (500–1000 µg/mL) were compared (* p < 0.05; ** p < 0.01). PI—propidium iodide.