Table 5.
Cell viability of P. amarus and its compounds towards the RBL-2H3 cell line.
| Concentration | 2.5 µg/mL | 5 µg/mL | 10 µg/mL | 25 µg/mL | 50 µg/mL | 100 µg/mL |
|---|---|---|---|---|---|---|
| Ketotifen fumarate (positive control) |
91.93 ± 6.16 | 90.09 ± 3.89 | 86.75 ± 6.47 | 87.37 ± 1.17 | 83.84 ± 4.10 | 28.89 ± 4.87 |
| P. amarus | 80.81 ± 12.36 | 77.04 ± 5.55 | 67.25 ± 5.20 | 74.22 ± 2.69 | 76.59 ± 2.23 | 75.18 ± 10.50 |
| Phyllanthin (1) | 92.02 ± 1.13 | 76.57 ± 3.77 | 84.30 ± 6.83 | 82.10 ± 4.03 | 74.18 ± 7.99 | 53.48 ± 0.65 |
| Hypophyllanthin (2) | 92.96 ± 9.69 | 90.95 ± 10.40 | 114.35 ± 8.89 | 62.46 ± 0.56 | 40.58 ± 4.17 | 28.12 ± 4.13 |
| Niranthin (3) | 103.79 ± 5.79 | 79.44 ± 8.96 | 96.46 ± 7.33 | 85.37 ± 11.62 | 96.63 ± 0.63 | 86.26 ± 12.41 |
| Corilagin (4) | 87.10 ± 4.31 | 81.10 ± 14.81 | 93.71 ± 15.36 | 102.69 ± 12.10 | 104.43 ± 7.35 | 100.75 ± 7.2 |
| DMSO (solvent) |
83.25 ± 14.49 | 82.12 ± 8.73 | 88.94 ± 9.52 | 97.73 ± 6.65 | 83.74 ± 14.92 | 74.56 ± 15.31 |