Table 4.

Multivariable regression of APOE ɛ4status and T1 and DTI brain age gap.

Brain Age Gap	Comparison Groups
	APOE-ɛ4(−) vs. APOE-ɛ4(+)
	B	SE	p-Value	R2
T1w-based:				0.054
-APOE ɛ4	0.790	1.404	0.58
-Age (per year)	0.032	0.050	0.52
-Sex	1.791	1.424	0.21
-Head coil	−3.328	1.508	0.03
DTI-based:				0.119
-APOE ɛ4	−2.564	1.563	0.1
-Age (per year)	0.131	0.056	0.02
-Sex	−3.614	1.586	0.02
-Head Coil	−3.425	1.679	0.04