. 2021 Jan 22;10(3):418. doi: 10.3390/jcm10030418

Table 5.

APOE ɛ4 status on mean values of neuroanatomic volume measurements per region of interest (ROI).

ROI	APOE-ɛ4(−) (n = 75)		APOE-ɛ4(+) (n = 48)		p-Value
ROI	Mean mm³	SD mm³	Mean mm³	SD mm³
Total ICV	1.584767	152.613	1.571603	150.490	0.64
Total gray volume	662.282	66.495	664.349	64.095	0.87
Cortex volume	491.343	51.833	492.455	47.444	0.91
L Accumbens area	645	137	688	135	0.09
R Accumbens area	649	125	636	131	0.59
L Amygdala	1597	233	1607	195	0.81
R Amygdala	1843	249	1852	240	0.84
Brainstem	21,267	2108	20.485	2514	0.06
L Caudate	3815	573	3954	517	0.18
R Caudate	3999	629	4195	568	0.08
CC-posterior	990	147	982	168	0.78
CC-mid-posterior	432	91	402	89	0.08
CC-central	437	78	414	84	0.13
CC-mid-anterior	456	94	442	79	0.39
CC-anterior	905	144	890	141	0.58
L Hippocampus	4555	542	4480	478	0.44
R Hippocampus	4551	467	4576	446	0.78
L Pallidum	1337	296	1308	312	0.61
R Pallidum	1596	280	1558	291	0.47
L Putamen	60,441	892	6009	1009	0.84
R Putamen	5946	796	6009	856	0.68
L Thalamus	8612	1183	8603	1068	0.97
R Thalamus	6983	913	6975	900	0.96
L lateral Ventricle	9760	5507	10.717	6399	0.38
R lateral Ventricle	9068	6041	8983	4994	0.93

Abbreviations: ICV = intracranial volume, L = left, R = right, CC = corpus callosum, p-values are from the mean comparisons by the independent T-tests.