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(A) Lack of endothelin A receptor (ETAR) expression in the tubular epithelium, glomeruli, and interstitium (200×, hematoxylin). (B) Mild to moderate expression of ETAR in glomeruli with mild to moderate reactivity in the tubular epithelium. Note the focal enhanced immunoreactivity of ETAR in the kidney interstitium (200×, hematoxylin). (C) Mild to moderate immunoreactivity in a glomerulus with high ETAR expression in the tubular epithelium (200×, hematoxylin).
