Skip to main content
. 2021 Jan 22;22(3):1075. doi: 10.3390/ijms22031075

Table A4.

Top 25 upregulated and downregulated genes in high risk patients compared to low risk patients. Abbreviations: FC = fold change; FDR = false discovery rate (Benjamini–Hochberg).

Upregulated Genes Downregulatd Genes
Gene Log2 FC FDR Gene Log2 FC FDR
CHGA 4.35 2.17×10−24 CYP1A2 −3.56 2.76×10−22
CA9 3.95 1.17×10−24 CYP3A4 −2.91 2.30×10−18
DMBT1 3.91 2.00×10−26 C15orf43 −2.85 9.56×10−18
UCHL1 3.75 1.18×10−37 INS-IGF2 −2.84 2.23×10−11
HMGA2 3.53 1.13×10−15 SLC6A2 −2.79 8.92×10−08
HAVCR1 3.51 2.76×10−22 LUZP2 −2.72 5.82×10−14
AGR2 3.29 2.70×10−11 HAMP −2.64 1.34×10−16
MUC5B 3.25 1.90×10−14 AQP6 −2.33 2.96×10−10
CXCL5 3.14 3.34×10−17 ECEL1 −2.32 7.64×10−08
SLC7A10 3.09 1.74×10−14 CRHBP −2.29 8.14×10−20
CLDN18 3.06 3.68×10−17 WNT3A −2.28 7.03×10−07
UGT1A7 3.05 6.82×10−12 RGSL1 −2.26 4.54×10−08
IL20RA 3.03 3.14×10−13 CLEC4G −2.19 1.31×10−12
MEP1A 2.97 8.12×10−16 FCN2 −2.12 9.01×10−12
WNT7B 2.95 7.85×10−15 CYP1A1 −2.08 6.53×10−10
CDH17 2.84 9.89×10−14 STAB2 −2.07 5.00×10−11
CHGB 2.65 4.34×10−09 WBSCR17 −2.02 2.13×10−10
ALDH3B2 2.64 3.55×10−12 RSPO3 −2.00 5.77×10−10
SLC34A2 2.64 3.15×10−10 MT1G −1.98 1.49×10−09
MMP1 2.63 1.36×10−25 CYP26A1 −1.96 3.24×10−12
MMP10 2.57 1.34×10−14 COLEC10 −1.92 4.44×10−15
MMP12 2.57 7.72×10−16 RSPO2 −1.88 1.08×10−06
CHRNA1 2.52 2.30×10−15 HEPN1 −1.87 4.50×10−05
SCG3 2.50 2.17×10−14 TG −1.85 5.41×10−13
AFP 2.46 1.71×10−11 SAA2 −1.84 1.15×10−08