Table 1.
Characteristics of the study population from Begleitende Evaluierung innovativer Testverfahren zur Darmkrebs-Früherkennung (BLITZ) participants in screening colonoscopy.
Group | BLITZ (Screening) | |||
---|---|---|---|---|
PEA, LC/MRM-MS and QMA Assays | IpA Assays | |||
Total | CRC | Controls | CRC | Controls |
N (%) | N (%) | N (%) | N (%) | |
56 | 99 | 30 | 30 | |
Age in years | ||||
50–59 | 10 (18) | 20 (20) | 5 (16) | 5 (16) |
60–69 | 28 (50) | 49 (50) | 14 (47) | 14 (47) |
70–79 | 18 (32) | 30 (30) | 11 (37) | 11 (37) |
Mean | 66.0 | 65.4 | 66.2 | 66.2 |
Median | 65.0 | 66.0 | 64.5 | 64.5 |
SD | 5.8 | 6.9 | 6.9 | 6.9 |
Gender distribution | ||||
Male | 36 (64) | 63 (64) | 18 (60) | 18 (60) |
Female | 20 (36) | 36 (36) | 12 (40) | 12 (40) |
Stage distribution | ||||
Stage I | 17 (30) | - | 9 (30) | - |
Stage II | 6 (11) | - | 6 (20) | - |
Stage III | 26 (46) | - | 8 (27) | - |
Stage IV | 7 (13) | - | 7 (23) | - |
Early stage (I/II) | 23 (41) | - | 15 (50) | - |
Late stage (III/IV) | 33 (59) | - | 15 (50) | - |
Abbreviations: CRC, colorectal cancer; IpA, immunome protein array; LC/MRM-MS, liquid chromatography/multiple reaction monitoring–mass spectrometry; N, number; SD, standard deviation; PEA, proximity extension assay; QMA, quantibody microarray.