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. 2021 Jan 25;26(3):615. doi: 10.3390/molecules26030615

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Determination of DNA fragmentation in SK-BR-3 (a) and MCF-7 (b) cells; cells were incubated with betulin and its derivatives for 24 h; cytosolic DNA/histone complexes were measured by ELISA; results are expressed as fold change over control; each bar represents the mean ± SD; * p < 0.05 compared with control.