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Growth inhibition efficiency (IC50) of betulin (1) and its derivatives on two breast cancer cell lines after treatment for 72h; table shows arithmetic means ± SD.
| Compound | IC50 (µM) | |
|---|---|---|
| SK-BR-3 | MCF7 | |
| 1 | 7.93 ± 1.05 | 13.26 ± 0.75 |
| 2 | 3.83 ± 0.34 | n.d. |
| 3 | 2.89 ± 0.56 | n.d. |
| 4 | 2.12 ± 0.59 | 5.34 ± 0.03 |
| 5 | 3.49 ± 0.32 | 12.88 ± 0.96 |
