Table 1.
A summary of the oral cancer studies using Fourier transform infrared (FTIR) spectroscopy discussed in this review.
| Type of Study | Title of Study | References |
|---|---|---|
| Biochemical imaging and 2D classification of keratin pearl structures in oral squamous cell carcinoma | [84] | |
| In situ infrared histopathology of keratinization in human oral/oropharyngeal squamous cell carcinoma | [85] | |
| A study on the differences between oral squamous cell carcinomas and normal oral mucosas measured by Fourier transform infrared spectroscopy | [86] | |
| Distinguishing malignant from normal oral tissues using FTIR fiber-optic techniques | [87] | |
| Histological and microscopy FT-IR imaging study on the proliferative activity and angiogenesis in head and neck tumors | [88] | |
| Oral tissue studies | FT-IR microscopy imaging on oral cavity tumors, II. | [89] |
| Microimaging FT-IR of oral cavity tumors. Part III: Cells, inoculated tissues and human tissues. | [90] | |
| Infrared microspectroscopy of Oral Squamous Cell Carcinoma: Spectral signatures of cancer grading | [91] | |
| Fourier transform infrared imaging analysis in discrimination studies of squamous cell carcinoma | [92] | |
| Fourier-transform-infrared-spectroscopy based spectral-biomarker selection towards optimum diagnostic differentiation of oral leukoplakia and cancer | [93] | |
| FTIR-ATR and FT-Raman Spectroscopy for Biochemical Changes in Oral Tissue | [94] | |
| Spectral cytopathology: new aspects of data collection, manipulation and confounding effects | [95] | |
| Infrared micro-spectroscopy for cyto-pathological classification of esophageal cells | [96] | |
| Oral cell studies | Cancer Screening via Infrared Spectral Cytopathology (SCP): Results for the Upper Respiratory and Digestive Tracts | [97] |
| Chemometric analysis of integrated FTIR and Raman spectra obtained by non-invasive exfoliative cytology for the screening of oral cancer | [98] | |
| In vitro FTIR microspectroscopy analysis of primary oral squamous carcinoma cells treated with cisplatin and 5-fluorouracil: a new spectroscopic approach for studying the drug-cell interaction | [99] | |
| Oral cancer diagnostics based on infrared spectral markers and wax physisorption kinetics | [100] | |
| Fourier transform infrared for noninvasive optical diagnosis of oral, oropharyngeal, and laryngeal cancer | [106] | |
| Serum-based diagnostic prediction of oral submucous fibrosis using FTIR spectrometry | [107] | |
| Biofluid studies | A comparative profiling of oral cancer patients and high risk niswar users using FT-IR and chemometric analysis | [108] |
| Extracellular vesicles in head and neck cancer: A potential new trend in diagnosis, prognosis, and treatment | [110] | |
| FTIR-based spectrum of salivary exosomes coupled with computational-aided discriminating analysis in the diagnosis of oral cancer | [111] | |
| Tumor microenvironment study | Changes in the microenvironment of invading melanoma and carcinoma cells identified by FTIR imaging | [112] |