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. 2021 Jan 26;13(3):474. doi: 10.3390/cancers13030474

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The pathways of lipid metabolism. ABCA1, ATP-binding cassette transporter A1; ACAT1, acetyl-CoA acetyltransferase 1; ACC, acetyl-CoA carboxylase; Acetyl-CoA, acetyl-coenzyme A; ACLY, ATP citrate lyase; ACS, acyl-CoA synthetase; Acyl-CoA, acyl-coenzyme A; ATGL, adipose triglyceride lipase; CACT, carnitine acylcarnitine translocase; CE, cholesterol ester; CPT1, carnitine palmitoyltransferase 1; CPT2, carnitine palmitoyltransferase 2; DAG, diasylglycerol; DGAT, diglyceride acyltransferase; FA, fatty acid; FAO, fatty acid oxidation; FASN, fatty acid synthase; HMGCR, 3-hydroxy-3-methylglutaryl-CoA reductase; LD, lipid droplet; LDLR, low-density lipoprotein receptor; LXR, liver X receptor; LXRE, LXR response element; MUFA, monounsaturated fatty acid; PC, phosphatidylcholine; SCD, stearoly-CoA desaturase; SRE, sterol regulatory element; SREBP, sterol regulatory element-binding protein; SQLE, squalene epoxidase; TAG, triacylglycerol; TCA, tricarboxylic acid.