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. 2021 Jan 23;13(3):430. doi: 10.3390/cancers13030430

Table 1.

Human hallmark gene set enrichment of IQGAP1 DEGs.

Pathway P.Adj ES NES Size
INFγ response 0.004662 −0.53228 −2.77404 92
Apical junction 0.004662 −0.44445 −2.25531 78
Inflammatory response 0.004662 −0.58813 −3.02081 84
Il2_Stat5 signaling 0.004662 −0.4212 −2.14177 80
Complement 0.004662 −0.42784 −2.17532 81
Allograft rejection 0.004662 −0.55785 −2.83455 82
KRAS signaling UP 0.004662 −0.62089 −3.10098 73
UV response DN 0.004662 −0.52657 −2.58735 67
TNFα signaling via NFκB 0.004662 −0.56906 −2.80937 70
Epithelial mesenchymal transition 0.004662 −0.64204 −3.10811 63
Estrogen response early 0.004662 −0.50057 −2.37491 59
INFα response 0.004662 −0.47271 −2.12179 45
IL6 Jak Stat3 signaling 0.004662 −0.60951 −2.574 33
Estrogen response late 0.007924 −0.42778 −1.91355 44
Coagulation 0.007924 −0.46215 −2.02948 41
Myc targets V2 0.011409 0.481626 2.48835 32
Fatty acid metabolism 0.011897 0.30286 1.71898 46
Apoptosis 0.011897 −0.36188 −1.74708 62
Hypoxia 0.011897 −0.37568 −1.79535 60
DNA repair 0.013372 0.37213 2.35074 69
Myc targets V1 0.016632 0.41489 2.90611 102
Mitotic spindle 0.016632 −0.32065 −1.71067 103
Myogenesis 0.017405 −0.37748 −1.71929 49
Oxidative phosphorylation 0.017405 0.508354 3.58833 113
TGFβ signaling 0.017405 −0.44961 −1.80892 28

P.Adj: adjusted p value; ES: enrichment score; NES: normalized enrichment score.