Table 1.
Peptide nucleic acid (PNA) probe sequences. Amino acids are denoted by uppercase letters, and PNA monomers are denoted by lowercase letters. DOTA is the chelator 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid, and AEEA is the PEG-based linker NH2-(PEG)2-CH2COOH (also referred to as 2-[2-(2-aminoethoxy)ethoxy]acetic acid).
| Name | Sequence | Reference | Mw [Da] |
|---|---|---|---|
| HP1 | G-G-G-S-S-a-g-t-c-t-g-g-a-t-g-t-a-g-t-c-E-K(DOTA)-AEEA-E-NH2 | [20] | 5396 |
| HP2 | DOTA-AEEA-S-S-g-a-c-t-a-c-a-t-c-c-a-g-a-c-t-E-E-Y-NH2 | [20] | 5158 |
| HP15 | G-S-S-c-c-t-g-g-t-g-t-t-g-a-t-g-a-t-E-K(DOTA)-AEEA-E-NH2 | New | 5273 |
| HP16 | DOTA-AEEA-S-S-a-a-c-a-c-c-a-g-g-E-E-Y-NH2 | New | 3582 |
| HP17 | DOTA-AEEA-S-S -a-t-c-a-a-c-a-c-c-a-g-g-E-E-Y-NH2 | New | 4375 |
| HP18 | DOTA-AEEA-S-S-a-t-c-a-t-c-a-a-c-a-c-c-a-g-g-E-E-Y-NH2 | New | 5167 |