Table 2.

Studies on cumulative cancer risks in Peutz–Jeghers syndrome.

Study	N	gac	smbc	crc	Gastroint. Cancer	pac	bc	utc	ovc	cx	Gynecol. Cancer	All	At Age (Years)
Gardielo et al., 2000 [12], meta-analysis	210	29	13	39		36	54	9	21	10		93	64
Hearle et al., 2006 [13], cohort study	419				57	11	45				18	85	70
Mehenni et al., 2006 [14], cohort study	149				63 *	18 #						67	70
Van Lier et al., 2011 [15], cohort study	133				51 **							76	70
Korsse et al., 2013 [16], cohort study	144					26							70
Resta et al., 2013 [17], cohort study	119			12		55	24			23		89	60–65
Ishida et al., 2016 [18], meta-analysis	583	24	10–14	36		29	19	47 ***	10			83	70
Chen et al., 2017 [19], cohort study	336			28								55	60

gac = gastric cancer; smbc = small bowel cancer; crc = colorectal cancer; gastroint. = gastrointestinal; pac = pancreas cancer; bc = breast cancer; utc = uterus cancer; ovc = ovary cancer; cx = cervix cancer; gynecol. = gynecological; * including biliary tract cancer; ** including pancreas and biliary tract cancer; *** including adenocarcinoma cervix; # at age 50 years.