ACPAs	anti-citrullinated peptide antibodies
AD	Alzheimer’s disease
BBB	blood–brain barrier
BDI	Beck Depression Inventory
bDMARDs	biological DMARDs
BDNF	brain-derived neurotrophic factor
BVRT	Benton Visual Retention Test
csDMARDs	conventional synthetic DMARDs
CSF	cerebrospinal fluid
DAS-28	Disease Activity Score
DHEADHEA-S	dehydroepiandrosterone dehydroepiandrosterone sulfate
EULAR	European League Against Rheumatism
fMRI	functional MRI
GDNF	glial-cell-line-derived neurotrophic factor
GFAP	glial fibrillary acidic protein
MBP	myelin basic protein
MCI	mild cognitive impairment
MHC	major histocompatibility complex
MMSE	Mini-Mental State Examination
MoCA	Montreal Cognitive Assessment
MOG	myelin oligodendrocyte glycoprotein
MRI	magnetic resonance imaging
NKT	natural killer T cell
NO	nitric oxide
NSAIDs	non-steroidal anti-inflammatory drugs
PBMCs	peripheral blood mononuclear cells
poly I:C	polyinosinic:polycytidilic acid
RA	rheumatoid arthritis
RF	rheumatoid factor
S100β	S100 calcium-binding β
Sal	salidroside
SHH	sonic hedgehog
SLE	systemic lupus erythematosus
STAIT/S TNF	State-Trait Anxiety Inventory Tumor necrosis factor
TMT	Trail-Making Test
TrkB	tropomyosin-related kinase B
tsDMARDs	targeted synthetic DMARDs
TTR	serum paraoxonase
VST	Victoria Stroop Test
WAIS	Wechsler Adult Intelligence Scale