Table 2.

Diagnostic criteria for drug-induced hypersensitivity syndrome (DiHS) established by the Japanese Consensus Group *** [13].

1	Maculopapular rash developing >3 weeks after starting with a limited number of drugs
2	Prolonged clinical symptoms 2 weeks after discontinuation of the causative drug
3	Fever >38 °C
4	Liver abnormalities (alanine aminotransferase >100 U/L)
5	Leucocyte abnormalities (at least one present)
a	Leucocytosis (>11 × 109/L)
b	Atypical lymphocytosis (>5%)
c	Eosinophilia (>1.5 × 109/L)
6	Lymphadenopathy
7	HHV-6 reactivation

*** The diagnosis is confirmed by the presence of the seven criteria (typical DiHS) or of five criteria (atypical DiHS).