Table 3.
The percentage of injection dose per gram (%ID/g) of the 111ln-cyclic RGDfK-liposome or the 111ln-liposome in lymph nodes and the radioactivity proportion of lymph nodes to blood in the mice without human melanoma xenotransplantation.
Drug | 111ln-Cyclic RGDfK-Liposome | 111ln-Liposome | |
---|---|---|---|
Item | |||
jejunal lymph node (%ID/g) | 2.1 ± 0.1 | 2.3 ± 00.09 | |
inguinal lymph node (%ID/g) | 0.5 ± 00.01 | 0.7 ± 0.1 | |
axillary lymph node (%ID/g) | 0.7 ± 0.12 | 1.2 ± 00.09 | |
blood (%ID/g) | 1.1 ± 00.05 | 1.3 ± 00.07 | |
lymph node-to-blood ratio | jejunal to blood | 1.9 | 1.7 |
inguinal to blood | 0.45 | 0.5 | |
axillary to blood | 0.6 | 0.9 |