Skip to main content
. 2021 Jan 21;13(3):341. doi: 10.3390/polym13030341

Figure 13.

Figure 13

The scheme of preparation of ATRA-loaded lipid-polymer nanoparticles. The oil phase was formed by dissolving ATRA and PLGA in acetone. Then, the oil phase was slowly injected into poly(vinyl alcohol) (PVA) solution by homogenization. After the recovery by evaporation and centrifugation, the PNPs were hydrated with the lipid film. The CD133 aptamers were conjugated to the nanoparticles by the interaction of the maleimide on nanoparticles and the sulfhydryl groups of CD133 aptamers. Adopted from Gui et al. [220].