Table 1.
Features | Antibody | Aptamer |
---|---|---|
Specificity | High | High |
Size | Relatively high | Small |
Stability | Unstable | Stable |
Affinity | High | High |
Immunogenicity | High | No humoral response |
Potential target | Immunogenic molecules | Any target |
Production | In vivo | In vitro |
Cost | Expensive | Relatively cheap |
Modification | Limited | Almost unlimited |
Time to generate | ~6 months | ~3–7 weeks |
Renal separation | Slow | Fast |