Table 3.
The capability of LNPs as a drug carrier for several types of drugs.
| Loaded Drugs | Loading Capacity (%) | Encapsulation Efficiency (%) | Release (%) | References |
|---|---|---|---|---|
| Curcumin | - | 92 ± 4 | 34 (intestinal pH 7.4; 8 h) | [20] |
| ±80 (intestinal pH 7.4; 150 h) | ||||
| 8.7 (gastric pH 2; 4 h) | ||||
| ±25 (gastric pH 2; 150 h) | ||||
| Ovalbumin | - | 81.64 | 16.4 ± 4.2 (pH 7.4; 12 h) | |
| Resveratrol | >20 | > 90 | > 80 (pH 7.4; 50 h) | |
| Benzazulene | 8 ± 1 | 77 ± 10 | 90 (pH 5.5; 6 h) | [32] |
| 95 (pH 7.4; 6 h) | ||||
| Sorafenib | 7 ± 2 | 68 ± 19 | 61 (pH 5.5; 6 h) | |
| 100 (pH 7.4; 6 h) | ||||
| Doxorubicin | - | 67.5 ± 6 (In vitro) | 21.3 (pH 5.5; 4 h) | [26] |
| 49.4 ± 7 (Ex vitro) | 15.2 (pH 7.4; 4 h) | |||
| Doxorubicin | >12.5 | >60 | >50 (pH 5.5; 60 h) | [27] |
| >65 (pH 7.4; 60 h) | ||||
| Irinotecan | 13.61 ± 0.59 | 67.65 ± 1.95 | 22.11 ± 4.05 (pH 7.4; 2 h) | [30] |
| 43.84 ± 6.07 (pH 7.4; 8 h) | ||||
| 86.72 ± 7.05 (pH 7.4 72 h) |