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MTT assay in HOG (a,b) and SH-SY5Y (c,d) cells treated with increasing concentrations of CPZ (50–1000 µM) and their respective vehicles for 24 h (a,c) or 48 h (b,d). Cell damage is represented as the percentage of viability versus control. Data are the mean ± S.E.M of five independent experiments. Significant differences were analyzed by a one-way ANOVA followed by post-hoc Tukey’s test. * p < 0.05, ** p < 0.01, *** p < 0.001 compared to control.
