Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jan 25;22(3):1162. doi: 10.3390/ijms22031162

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Docking poses of selected compound 4k onto the active site of glycogen synthase kinase-3 beta (GSK-3β) (PDB ID: 1UV5). (A) Two-dimensional (2D) interaction data and residues of bound ligand 6-bromoindirubin-3′-oxime within the ATP pocket of the target. (B) 2D of the compound within the ATP pocket with the corresponding hydrogen bonding and aromatic interactions with residues. (C) Three-dimensional (3D) analysis of the target compound 4k mapped to the reference drug, i.e., 6-Bromoindirubin-3′-oxime.

Docking poses of selected compound 4k onto the active site of glycogen synthase kinase-3 beta (GSK-3β) (PDB ID: 1UV5). (A) Two-dimensional (2D) interaction data and residues of bound ligand 6-bromoindirubin-3′-oxime within the ATP pocket of the target. (B) 2D of the compound within the ATP pocket with the corresponding hydrogen bonding and aromatic interactions with residues. (C) Three-dimensional (3D) analysis of the target compound 4k mapped to the reference drug, i.e., 6-Bromoindirubin-3′-oxime.