Table 8.

Parameters for the expression of the biosynthesis of N-acetylaspartyl-glutamate in the substrate inhibition model of Michaelis–Menten by proton magnetic resonance spectroscopy (¹H-MRS) in the ASD (n = 22) and TD (n = 43) groups.

Brain Region	Vmax [μM/min]	ASD KM [mM]	Ki [mM]	R2	Vmax [μM/min]	TD KM [mM]	Ki [mM]	R2
ACC
NAA	1.1 × 108	5.80 × 106	5.59 × 10−8	−27.05	2.8 × 108	3.2 × 107	3.0 × 10−8	−86.74
Glu	1.6 × 108	5.92 × 106	4.44 × 10−8	−9.76	3.0 × 108	5.1 × 107	6.0 × 10−8	−16.96
PCC
NAA	16.27	2.92 × 10−3	1.35	−23.95	---	---	---	---
Glu	19.13	4.68 × 10−3	1.04	−14.72	11.29	4.73 × 10−4	15.26	−20.33