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. 2021 Jan 23;13(3):423. doi: 10.3390/cancers13030423

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Correlation of biomarkers with response to chemotherapy for patients who received (ZA+) or not (ZA−) zoledronic acid. (A) Representation of response to chemotherapy (GR: good responders; PR: poor responders) in relation to immunohistochemical analysis (% of cells positive) of CD8 (left panel), CD163 (middle panel) and CD68 (right panel). (B) Representation of response to chemotherapy (GR: good responders; PR: poor responders) in relation to serum analysis of CSFR-1 at diagnosis (left panel), surgery (middle panel) and the difference of CSF-1R levels between diagnosis and surgery (right panel). (C) Representation of response to chemotherapy (GR: good responders; PR: poor responders) in relation to serum analysis of TRAP at diagnosis (left panel), surgery (middle panel) and the difference of TRAP levels between diagnosis and surgery (right panel).