Table 6.

Ongoing gene therapy clinical trials for nvAMD.

Trial Name	Targeted Gene	Vector	Sponsor
NCT01494805 [257]	sFLT01	AAV-2	Adverum Biotechnologies, Inc. (Redwoodcity, CA, USA)
NCT03585556 [258]	sCD59	AAV-2	Hemera Biosciences (Waltham, MA, USA)
NCT01024998 [254]	sFLT-1	AAV-2	Sanofi Genzyme (Cambridge, MA, USA)
NCT03748784 [259]	Aflibercept	AAV-2	Adverum Biotechnologies, Inc. (Redwoodcity, CA, USA)
NCT03066258 [253]	Anti-VEGF Fab	AAV-8	Regenxbio Inc.(Rockville, MD, USA)
NCT01678872 [256]	Endostatin/Angiostatin	EIAV	Oxford BioMedica (Oxford, UK)
NCT00109499 [255]	PEDF	AAV5	GenVec (Gaithersburg, MD, USA)
NCT03999801 [260]	Monoclonal antibody fragment	AAV-8	Regenxbio Inc. (Rockville, MD, USA)