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. 2021 Jan 24;22(3):1145. doi: 10.3390/ijms22031145

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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NAD(P)(H)-derived pyridone catabolites. An additional route to the triphosphate from the monophosphate ribosylated pyridone generated from the dinucleotides can also be envisaged. NAD(P)(H): nicotinamide adenine dinucleotide (phosphate) (reduced form); NAD(P)O: hyper- oxidized forms of NAD(P) containing pyridone moieties; PYR-TP: pyridone riboside triphosphate; PYR: pyridone riboside; The 2, 4, and 6 positions of the carbonyl unit are indicated in the abbreviation; N-Me-PY: N-methyl pyridone.