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Dose-dependent sensitivity of HepG3 cells to continuous 4PYR treatment. HEK239T (A) and HepG3 (B) cells were exposed to 25, 50, 75, 100, and 150 µM continuously for 72 h. CellTiter-FluorTM Viability assay was performed with results expressed as the mean fluorescence intensity relative to control, vehicle-treated cells (% viability) ± SEM. Statistical significance: ** p < 0.005, **** p < 0.0001.
