Table 3.
Hematological and CSF parameters on admission in all 123 included patients with confirmed Japanese encephalitis virus infection
| Variable | Total (n = 123) | Children (n = 70) | Adults (n = 53) | P-value* |
|---|---|---|---|---|
| Hematological parameters | ||||
| Hematocrit (%), median (IQR) | 38.0 (35.0–42.0) | 36.5 (35.0–40.0) | 40.0 (35.5–45.0) | 0.007 |
| (n = 105) | (n = 59) | (n = 46) | ||
| White blood cell count (cells/mm3), median (IQR) | 12,000 (9,300–17,500) | 13,000† (10,000–18,900) | 11,645 (7,820–15,900) | 0.095 |
| (n = 109) | (n = 61) | (n = 48) | ||
| Neutrophils (%), median (IQR) | 81 (71.2–89.4) | 81 (71.4–90.2) | 82 (69.7–89.0) | 0.789 |
| (n = 100) | (n = 57) | (n = 43) | ||
| Lymphocytes (%), median (IQR) | 16.2 (7.8–24.1) | 17.0 (8.3–24.6) | 14.5 (7.2–21.5) | 0.757 |
| (n = 104) | (n = 60) | (n = 44) | ||
| Glycemia (mmoL/L), median (IQR) | 6.4 (5.5–8.2) | 6.3 (5.5–8.7) | 6.6 (5.5–7.9) | 0.738 |
| (n = 122) | (n = 70) | (n = 52) | ||
| CSF parameters | ||||
| Opening pressure (cmH20), median (IQR) | 20 (16–24.6) | 18.0 (14–24) | 22.0 (18.8–25) | 0.013 |
| (n = 121) | (n = 69) | (n = 52) | ||
| White cell count (cells/mm3), median (IQR) | 75 (30–125) | 50 (20–125) | 150 (50–320) | < 0.001 |
| (n = 123) | (n = 70) | (n = 53) | ||
| Neutrophils (%), median (IQR) | 20 (6–52) | 18 (9–52) | 21 (5–50) | 0.955 |
| (n = 123) | (n = 70) | (n = 53) | ||
| Lymphocytes (%), median (IQR) | 70 (28–88) | 66 (28–87) | 70 (28–90) | 0.698 |
| (n = 123) | (n = 70) | (n = 53) | ||
| Glucose (mmoL/L), median (IQR) | 3.6 (2.5–4.5) | 3.4 (2.4–4.5) | 3.6 (2.6–4.5) | 0.800 |
| (n = 106) | (n = 58) | (n = 48) | ||
| Protein (g/L), median (IQR) | 0.7 (0.3–1.1) | 0.5 (0.3–1.0) | 0.7 (0.5–1.2) | 0.028 |
| (n = 106) | (n = 58) | (n = 48) | ||
CSF = cerebrospinal fluid. Data shown as the number (%) unless indicated. Children: < 15 years; adults: ≥ 15 years.
*
Wilcoxon rank-sum test was used.
†
NB: no children were aged < 2 years old.