Figure 4.

Venn diagram of all proteins detected in human studies. On the left, the Venn diagram for human studies including Vella et al. fraction 2. On the right, including Vella et al. fraction 3. Gallart-Palau et al. detected 60.6% of proteins as unique, sharing 12.9% of proteins with the data set of fraction 2 from Vella et al., and 3.4% with Huang et al. The latter detected 2.6% of proteins as unique while sharing with Vella’s fraction 2 the 2.4% of detected proteins. Fraction 2 from Vella et al. accounts the 5.7% of proteins as unique. 12.4% of all proteins are shared among the three studies. When considering Vella’s fraction 3, Gallart-Palau et al. detected 64.2% of proteins as unique, sharing 9.6% of proteins with the data set of fraction 3 from Vella et al., and 7.6% with Huang et al. The latter detected 4.3% of proteins as unique, sharing with Vella et al. fraction 3 0.8% of proteins detected. Fraction 3 from Vella et al. presents 5.3% of proteins as unique. 8.2% of all proteins are shared among the three studies.