Table 2.
Baseline body composition, muscle strength, and physical performance of rheumatoid arthritis patients.
| Total (n = 83) |
Control (n = 18) |
TNFi (n = 47) |
Non-TNFi (n = 18) |
p | p a | |
|---|---|---|---|---|---|---|
| Total fat mass (kg) | 24.4 ± 11.5 | 26.5 ± 12.8 | 25.3 ± 12.2 | 20.2 ± 7.1 | 0.19 | 0.33 |
| Total fat mass (%) | 31.5 ± 8.9 | 30.2 ± 10.9 | 32.8 ± 8.3 | 29.6 ± 7.9 | 0.34 | 0.33 |
| FMI (kg/m2) | 9.3 ± 4.7 | 9.5 ± 5.3 | 9.4 ± 4.5 | 8.8 ± 4.9 | 0.85 | 0.78 |
| Trunk/peripheral FM ratio | 0.92 ± 0.28 | 1.00 ± 0.34 | 0.88 ± 0.22 | 0.95 ± 0.34 | 0.42 | 0.61 |
| VAT (cm2) | 100 [51; 159] | 141 [80; 179] | 90 [51; 137] | 98 [51; 139] | 0.28 | 0.28 |
| SAT (cm2) | 288 [212; 408] | 317 [243; 494] | 291 [212; 449] | 670 [196; 348] | 0.49 | 0.57 |
| VAT/SAT ratio | 0.30 [0.24; 0.46] | 0.32 [0.25; 0.67] | 0.29 [0.23; 0.36] | 0.30 [0.24; 0.51] | 0.30 | 0.15 |
| Total lean mass (kg) | 51.2 ± 12.1 | 58.7 ± 13.7 | 49.6 ± 10.8 | 47.7 ± 11.0 | 0.009 | 0.012 |
| FFMI (kg/m2) (n = 82) | 18.5 ± 3.0 | 20.2 ± 3.3 | 18.1 ± 2.9 | 17.8 ± 2.1 | 0.037 | 0.050 |
| SMI (kg/m2) | 7.9 ± 1.5 | 8.7 ± 1.7 | 7.7 ± 1.4 | 7.5 ± 1.1 | 0.026 | 0.042 |
| FMI/SMI ratio | 1.18 ± 0.52 | 1.11 ± 0.61 | 1.21 ± 0.48 | 1.18 ± 0.55 | 0.63 | 0.82 |
| Handgrip strength (kg) (n = 70) | 15.9 ± 11.4 | 23.7 ± 13.6 | 13.5 ± 8.9 | 13.8 ± 12.1 | 0.023 | 0.017 |
| 6 MWT (meters) (n = 64) | 455 [373; 540] | 485 [420; 511] | 435 [370; 540] | 490 [370; 540] | 0.83 | 0.78 |
| Sedentary (h/week) (n = 57) | 42 [21; 70] | 28 [21; 56] | 42 [21; 84] | 42 [28; 53] | 0.50 | 0.69 |
Data are presented as mean ± standard deviation or as median [interquartile range]. FFMI: fat-free mass index; FM: fat mass; FMI: fat mass index; SAT: subcutaneous adipose tissue; 6 MWT: 6-min walk test; SMI: skeletal muscle mass index; TNFi: tumor necrosis factor inhibitor; VAT: visceral adipose tissue. p: unadjusted comparisons; p a: adjusted comparisons on baseline characteristics: age, rheumatoid arthritis duration, erosive rheumatoid arthritis, and glucocorticoids.