Table 2.

Agents that can be used to treat the consequences of physiological or premature ovarian aging.

Agent	Administration	Mechanisms of Action	References
GH	Subcutaneous	Activation of cell-signaling pathways acting	[26,27,28,29,30,31,32]
		against oxidative stress
		Possible activation of DNA damage repair
Melatonin	Oral	Direct antioxidant	[33,34,35,36]
		Indirect antioxidant (signaling pathway modulator)
		Anti-inflammatory agent
		Immunomodulator
Coenzyme Q10	Oral	Direct antioxidant	[37,38,39]
Vitamin C	Oral	Direct antioxidant	[40]
Vitamin E	Oral	Direct antioxidant	[40]
Folic acid	Oral	Direct antioxidant	[40]