Figure 1.

(a) List of the model peptides investigated. Heptapeptide sequences a central motif -EVX- with X = L, F, A, or G. For each of the sequences, the corresponding relative frequency of occurrences between globular and transmembrane β-proteins are given. (b) Panels of TOCSY spectra of the model -EVX- peptides from left to right: AEVLEVG (black), AEVFEVG (red), AEVAEVG (blue), and AEVGEVG (green). The one-dimensional spectra on the top of each spectrum identify the corresponding chemical shift assignments.