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. 2021 Feb 6;21:125. doi: 10.1186/s12885-021-07833-5

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Diallyl thiosulfinate and dexamethasone (DATS+Dex) cotreatment inhibited proliferation and colony formation of multiple myeloma (MM) side population (SP) cells. a Effect of DATS, Dex, and DATS+Dex treatments on proliferation of MM SP cells detected using MTS analysis at 0, 24, 48, 72 h after treatment. b Bar represents cell numbers of colonies formed in SP cells after treatment with DATS, Dex, or DATS+Dex. c Representative image of colony formation by SP cells after treatment with DATS, Dex, or DATS+Dex. d Representative image of spheroids formation by SP cells after treatment with DATS, Dex, or DATS+Dex (magnification, × 100). ***P < 0.001 vs normal group, ^&P < 0.05 and ^&&&P < 0.001 vs DATS group, and ^###P < 0.001 vs Dex