Cy	cyclosphosphamide
DDR	DNA damage response
AKT	protein kinase B
FOXO3a	forkhead box O3
PBS	phosphate-buffered saline
4-OH-Cy	4-hydroperoxy-cyclophosphamide
IF	immunofluorescence
MCF7	Michigan Cancer Foundation-7
MEF	mouse embryonic fibroblasts
γH2AX	phosphorylated (Ser319) of histone 2AX
DNA-PK	DNA-dependent protein kinase, catalytic subunit
PARP	poly (ADP-ribose) polymerase
POF	premature ovarian failure
DSBS	double strand breaks
ATP	adenosine triphosphate
CML	chronic myeloid leukemia
IHC	immunohistochemistry
DMSO	dimethyl sulfoxide
WB	Western blotting