Figure 9.

The extracellular flux analysis pattern of macrophages from FcgRIIb-/- lupus mice and wild-type (FcgRIIb+/+) mice after 3 h of the incubation by media control (Media), a single LPS stimulation (N/LPS), and the twice LPS stimulation (LPS/LPS) as demonstrated by mitochondrial stress test (a pattern of oxygen consumption rate, respiratory capacity, and respiratory reserve) (A–C) and glycolysis stress test (a pattern of extracellular acidification rate, glycolysis and glycolysis capacity) (D–F). Independent triplicate experiments were performed. 2-DG, 2-Deoxy-D-glucose; FCCP, carbonyl cyanide-4-(trifluoromethoxy) phenylhydrazone.