TABLE 3.
Effect of peanut skin extracts of cultivars on lipid peroxidation and antioxidant enzyme activities in HepG2 cells
| Sample | 1MDA | 2GR | 3GPx | 4CAT | 5SOD |
|---|---|---|---|---|---|
| Control | 0.37 ± 0.05 | 4.78 ± 0.24 | 28.22 ± 1.09 | 11.49 ± 1.19 | 2.7 ± 0.13 |
| TBHP | 0.80 ± 0.03*** | 13.39 ± 0.79*** | 78.59 ± 3.63*** | 29.75 ± 1.67*** | 10.26 ± 0.40*** |
| TBHP + KME 10 | 0.58 ± 0.02b | 9.25 ± 1.16a | 30.98 ± 1.50b | 15.86 ± 0.60b | 3.93 ± 0.09b |
| TBHP + SME 10 | 0.49 ± 0.01c | 6.39 ± 0.66b | 25.48 ± 1.06c | 10.74 ± 0.35c | 2.98 ± 0.05d |
| TBHP + DME 10 | 0.45 ± 0.02d | 6.13 ± 0.39b | 20.19 ± 1.07d | 9.41 ± 0.46d | 3.21 ± 0.02c |
| TBHP + HME 10 | 0.63 ± 0.02a | 10.49 ± 0.33a | 38.79 ± 1.43a | 19.51 ± 0.90a | 4.86 ± 0.16a |
Lipid peroxidation of 1malondialdehyde (MDA, nmol mg protein) and antioxidant enzyme activity of 2glutathione reductase (GR, μmol min mg−1 protein), 3glutathione peroxidase (GPx, μmol min mg−1 protein), 4catalase (CAT, μmol min mg−1 protein), and 5SOD, unit mg‐1 protein) were evaluated in HepG2 cells treated for 6 hr with the samples, followed by treatment for 4 hr with 500 μM TBHP. Values are means ± SD (n = 3).
Significant at ***p < .001