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JCo extract enhanced 5‐FU induced cytotoxicity in esophageal cancer cells. Cells were treated with a combination of (a) JCo extract (20, 40, or 80 μg/ml) with or without 0.5 μg/ml 5‐FU; 5‐FU (0, 0.625, 1.25, 2.5 μg/ml) combined with or without 30 μg/mL JCo extract for 48 hr, and cell viability was measured via an MTT assay. (b) The results were analyzed using CompuSyn to calculate the normalized isobologram
