TABLE 4.

PASS prediction of standard drug and selected bioactive compounds of the aerial part of Piper nigrum

Biological Activity	Molecules
	Cepharadione A		Paprazine		Pellitorine		Piperine		Piperolactam D		Sylvamide		10‐Tricosanone
	Pa	Pi	Pa	Pi	Pa	Pi	Pa	Pi	Pa	Pi	Pa	Pi	Pa	Pi
Antidepressant	0.652	0.171	—	—	0.230	0.040	0.533	0.016	0.832	0.088	0.250	0.016	0.925	0.004
Anxiolytic	0.424	0.030	0.552	0.041	0.573	0.042	0.372	0.146	0.393	0.083	—	—	0.592	0.010
Antipyretic	0.045	0.025	0.264	0.027	0.481	0.042	—	—	—	—	0.496	0.039	0.656	0.019
Thrombolytic	—	—	0.601	0.072	0.622	0.007	0.172	0.115	0.713	0.116	0.050	0.045	0.713	0.018