Table 2.

Overview of blood and skin SMR analyses detailing tissue-specific and common BCC susceptibility genes

Tissue	Number of SMR genes	Sample size	Number of probes tested	P value threshold of multiple correction
Blood (eQTLGen)	46	31,684	15,652	3.19E−06
Skin_Sun_Exposed (GTEx)	25	243	6557	7.63E−06
Skin_Not_Sun_Exposed (GTEx)	21	216	5252	9.52E−06
Whole_Blood (GTEx)	20	360	4459	1.12E−05
Overall number of unique elements	63	/	/	/
Tissue	Number of overlapping genes	Gene name
Blood (eQTLGen)  Skin_Not_Sun_Exposed (GTEx)  Skin_Sun_Exposed (GTEx)  Whole_Blood (GTEx)	7	SPIRE2, CDK10, HLA-DRB1, HLA-DQA2, AL133458.1, RNASET2, CASP8
Blood (eQTLGen)  Skin_Not_Sun_Exposed (GTEx)  Skin_Sun_Exposed (GTEx)	1	ALS2CR12
Blood (eQTLGen)  Skin_Sun_Exposed (GTEx)  Whole_Blood (GTEx)	1	SPATA2L
Skin_Not_Sun_Exposed (GTEx)  Skin_Sun_Exposed (GTEx)  Whole_Blood (GTEx)	2	HLA-DOB, HLA-DRB6
Blood (eQTLGen)  Skin_Sun_Exposed (GTEx)	3	CLPTM1L, RP11-104N10.1, ALKBH5
Blood (eQTLGen)  Skin_Not_Sun_Exposed (GTEx)	3	SMC2, TGM3, NCOA6
Blood (eQTLGen)  Whole_Blood (GTEx)	7	RCC2, SPG7, PADI6, SPATA33, MAP1LC3A, CDKN2B, AP003774.1
Skin_Not_Sun_Exposed (GTEx)  Skin_Sun_Exposed (GTEx)	7	DBNDD1, TCF19, ASIP, PSORS1C3, HLA-DQA1, KRT6C, POU5F1
Tissue	Number of unique genes	Gene name
Blood (eQTLGen)	24	VDR, RP1-167A14.2, GGT7, IRF4, EIF2S2, TAP2, TRPC4AP, BNC2, AC007256.5, RP11-875O11.1, GAS8, RPS6KA2, ZNF276, CCR6, PES1, BACH2, CASP10, TP53, TP53INP2, CTLA4, AC137932.6, CHMP4B, STRADB, TICAM1
Skin_Sun_Exposed (GTEx)	4	FANCA, SEMA6C, CTSS, URAHP
Skin_Not_Sun_Exposed (GTEx)	1	FGFR1OP
Whole_Blood (GTEx)	3	CHMP1A, HLA-DRB9, SPAG1

Table revealing the number of SMR genes, sample size, number of probes tested, and multiple correction threshold in each tissue and the SMR genes unique to each tissue-gene dataset and list of SMR genes common among datasets. In the eQTLGen dataset, the gene name SPATA33 is aliased as C16orf55. To ease gene comparison analyses, C16orf55 was changed to SPATA33 in the eQTLGen results